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Investopedia
Insmed Stock More Than Doubled In Value Tuesday—Here’s Why
~1.1 mins read

Insmed (INSM) shares more than doubled in value Tuesday after the biopharmaceutical company announced positive results in a late-stage study of its experimental drug to reduce symptoms in patients with a rare lung disease.

The company said its Phase 3 trial of brensocatib demonstrated statistically significant reductions in the annualized rate of pulmonary exacerbations (PEs) for those suffering from non-cystic fibrosis bronchiectasis. PEs generally cause an increase in respiratory problems such as coughing and shortness of breath, as well as a decrease in lung function.

Lead study investigator James Chalmers noted that there is an urgent need for a therapy that can reduce PEs for people with bronchiectasis, and that brensocatib “could offer a completely new approach to managing this difficult-to-treat patient population.”

Insmed said that based on these results, it plans to file an application in the fourth quarter with the Food and Drug Administration (FDA) for use of brensocatib in patients with bronchiectasis. It added that pending that approval, it hopes to have the medicine on the market in mid-2025, followed by launches in Europe and Japan in the first half of 2026.

Shares of Insmed more than doubled Tuesday to close at $48.06 per share. With Tuesday’s news, they've advanced over 55% since the start of the year.

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Healthwatch
A Bird Flu Primer: What To Know And Do
~6.0 mins read

A weathered sign with red background and big white and black letters spelling out bird flu

A bird flu strain that began circulating in 2020 continues to evolve globally and locally within the United States. If you're wondering what this means, understanding the basics — what bird flu is, how it spreads, whether foods are safe, and prevention tips — can help. More information will come in as scientists learn more, so stay tuned.

1. What is bird flu and how does it spread?

Bird flu, or avian flu, is a naturally occurring illness. Just as certain flu viruses spread among humans, Type A influenza viruses often spread among wild birds. The strain of virus circulating now is H5N1, named for two proteins on its surface.

Avian flu infections are highly contagious. Infection often spreads first among wild water birds, such as ducks, geese, and gulls, and shore birds, such as plovers and sandpipers. The viruses are carried in their intestines and respiratory tract and shed in saliva, mucus, and feces. Wild birds can easily infect domestic poultry, such as chickens, turkeys, and ducks.

Some bird species, including ducks, may carry and spread infection without appearing sick. Domestic flocks are more likely to sicken and possibly die from bird flus. However, not all avian flu viruses are equally harmful:

  • Low pathogenic avian influenza (LPAI) may cause no signs of illness, or signs of mild illness like fewer eggs or ruffled feathers in domestic poultry.
  • Highly pathogenic avian influenza (HPAI) causes more severe illness and high rates of death in infected poultry. The current H5N1 virus is considered an HPAI.
  • 2. Can humans get bird flu?

    Yes, though this doesn't usually happen.

    When flu viruses mutate, they may be able to move from their original hosts — birds in this case — to humans and other animals. As of early April 2024, only two cases of bird flu in humans had been reported in the US since 2022. In May, an additional case was reported. Newer case numbers of bird flu will continue to be reported by the CDC, which offers weekly snapshots of influenza in the US.

    The virus may be introduced into the body through the eyes, nose, or mouth. For example, a person may inhale viral particles in the air (droplets, tiny aerosolized particles, or possibly in dust). Or they might touch a surface contaminated by the virus, then touch their eyes or nose. Bird flu in humans typically causes symptoms similar to seasonal flu, such as fever, runny nose, and body aches.

    3. Which animals have been affected by bird flu?

    A surprisingly long list of animals affected by the current H5NI bird flu infection includes:

  • wild birds, chickens, ducks, geese, and other domestic and commercial poultry in 48 states and more than 500 countries
  • livestock, such as dairy cows in nine states at this writing, and other farm animals
  • marine animals, such as seals, sea lions, and even dolphins
  • wild animals, such as foxes, skunks, and racoons, and some domestic animals, such as farm cats.
  • 4. Why are experts concerned about this bird flu outbreak?

    It might seem odd that there's been so much concern and news coverage about bird flu lately. After all, bird flu has been around for many years. We've long known it sometimes infects nonbird animal species, including humans.

    But the current outbreak is unique and worrisome for several reasons:

  • Fast, far-reaching spread. The virus has been found throughout the US, Europe, the Middle East, Southeast Asia, multiple sub-Saharan African countries, and even Antarctica.
  • Many species have been infected. Previously uninfected species have been affected, including animals in our food supply.
  • Economic impact. If large numbers of beef and dairy cows and chickens sicken or must be culled (killed) to contain outbreaks, this could have a major economic impact on farmers, agriculture businesses, and affected countries' economies. This could also mean higher prices at the grocery store.
  • Opportunities for exposure. Though only two human infections were reported in the US in recent years — both in people working with animals — the more exposure humans have to bird flu, the more chances the virus has to develop mutations that allow easier spread to humans.
  • Potential for fatalities. Severe strains of bird flu have led to H5N1 infections in nearly 900 people in 23 countries since 2003. More than half of these reported cases were fatal. Keep in mind that the math isn't straightforward. It's likely that many more cases of bird flu in humans occurred, yet people experiencing few or no symptoms or those not tested weren't counted, so lethality is likely overestimated.
  • New mutations. It's rare, but possible: If this H5N1 bird flu develops mutations that enable efficient person-to-person spread, bird flu could become the next human pandemic.
  • 5. Are milk, beef, chicken, and the rest of our food supply safe?

    Public health officials emphasize that the food supply is safe.

    But concern has understandably run high since the discovery that this outbreak has spread from birds to dairy cows for the first time. More alarming? A study found fragments of bird flu DNA — which is not the same as live virus — in 20% of commercially available milk in the US.

    So far, there's been no indication that bird flu found in pasteurized milk, beef, or other common foods can cause human illness. Even if live bird flu virus got into the milk supply, studies show that routine pasteurization would kill it. Initial tests did not find the virus in ground beef.

    Of course, if you are particularly concerned, you could avoid foods and beverages that come from animals affected by bird flu. For example, you could switch to oat milk or almond milk, even though there's no convincing scientific justification to do so now.

    6. What if you have pets or work with animals?

    Bird flu rarely spreads to pets. While that's good news, your pets could have exposure to animals infected with bird flu, such as through eating or playing with a dead bird. So, it's safest to limit your pet's opportunities to interact with potentially infected animals.

    If you work with animals, especially birds or livestock, or hunt, the Centers for Disease Control and Prevention (CDC) recommends precautions to minimize your exposure to bird flu.

    7. What else can you do to stay safe?

    The CDC recommends everyone take steps to avoid exposure to bird flu, including:

  • Avoid contact with sick or dead animals and keep pets away from them.
  • Avoid animal feces that may be contaminated by birds or bird droppings, as might be common on a farm.
  • Do not prepare or eat raw or undercooked food.
  • Do not drink raw (unpasteurized) milk or eat raw milk cheese or raw or undercooked foods from animals suspected of having bird flu infection.
  • Wear personal protective equipment (PPE), such as safety goggles, gloves, and an N95 face mask, when working near sick or dead animals or their feces.
  • Right now, available evidence doesn't support more dramatic preventive measures, such as switching to an all-plant diet.

    8. Is there any good news about bird flu?

    Despite all the worrisome news about bird flu, this recent outbreak may wind up posing little threat to human health. Virus strains may mutate to spread less efficiently or to be less deadly. Efforts are underway to contain the spread of bird flu to humans, including removing sick or exposed animals from the food supply and increased testing of dairy cattle before transport across state lines.

    And there is other encouraging news:

  • Some birds appear to be developing immunity to the virus. This could reduce the chances of continued spread between birds and other animals.
  • Developing a vaccine to protect cattle from bird flu may be possible (though it's unclear if this approach will be successful).
  • If spread to humans does occur, genetic tests suggest available antiviral medicines could help treat people.
  • So far, human-to-human transmission has not been detected. That makes it less likely that the H5N1 bird flu will become the next pandemic.
  • And if human infections with bird flu did become more common, researchers are working on human vaccines against bird flu using virus strains that match well with those causing the current outbreak.
  • 9. How worried should you be about bird flu?

    Though there's much we don't know, this much seems certain: bird flu will continue to change and pose challenges for farmers and health experts to stay ahead of it. So far, public health experts believe that bird flu poses little health risk to the general public.

    So, it's not time to panic about bird flu. But it is a good idea to take common sense steps to avoid exposure and stay current on related news.

    For updated information in the US, check the CDC website .

    Source: Harvard Health Publishing

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    Instablog9ja
    Nobody Knows The Secret To A Happy Marriage. Don’t Compare Your Marriage To Anyone’s Union — Reno Omokri
    ~0.2 mins read

    Media personality, Reno Omokri has advised people not to compare their marriages to anyone as he reiterated that no one knows the secret to a happy marriage.

    He made emphasis on his claim by highlighting a couple of successful individuals who have encountered fail marriages.

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    Investopedia
    Inflation Report This Week Could Be A Milestone On Path To Rate Cuts
    ~2.4 mins read

    If you’re waiting for lower interest rates on mortgages and other loans, a key inflation report this Friday could be a step in the right direction—though don’t expect rates to fall anytime soon.Consumer prices, as measured by the Bureau of Economic Analysis’ Personal Consumption Expenditures (PCE) measure, likely rose 0.3% in April from March, making for a 2.7% year-over-year gain, according to a survey of forecasters by Dow Jones Newswires and Both figures would be the same as in March, should those predictions hold.

    That could quell fears that price increases are reaccelerating, which were sparked by hotter-than-expected inflation in the first quarter. 

    More importantly, “core” inflation, which excludes volatile prices for food and energy, is predicted to have risen 0.2%, slowing down from the 0.3% rate in March. That’s significant because officials at the Federal Reserve pay close attention to core inflation. They see it as an indicator of broader inflation trends and consider it when setting the central bank’s monetary policy, which heavily influences interest rates on all kinds of loans.

    Since last July, Fed officials have held their key fed funds rate at its highest since 2001 in an effort to cool inflation. They’ve been waiting for signs that price increases are headed back down to a 2% annual rate before reducing the fed funds rate.Worse-than-expected inflation reports earlier this year threw cold water on hopes that rate cuts would come this summer, and forecasters are now focused on whether those cuts will start by the end of the year. For example, Fed Gov. Christopher Waller said last week that officials would have to see “several more months of good inflation data” before he would support rate cuts. 

    Fed officials have been trying to balance the need to control inflation with high interest rates against the damage those high rates are doing to the economy—and the possibility that they could slow the economy too much and start a recession.A PCE report in line with expectations would leave the Fed on track to cut rates starting at its meeting in December, economists at Deutsche Bank said in a research note.“Though an earlier cut is possible, it likely requires a string of more favorable inflation prints and some softening in the labor market or growth data,” Brett Ryan, senior U.S. economist Deutsche Bank, wrote, along with his colleagues. 

    Broader financial markets are more optimistic than Deutsche Bank about the timing of potential rate cuts. As of Tuesday, traders were pricing in a 55% chance of a cut by November, according to the CME Group’s FedWatch Tool, which forecasts rate movements based on fed funds futures trading data. 

    The report also will include data on consumer spending and income, which could also influence interest rate decisions and serve as a barometer for the financial health of U.S. households. Forecasters are expecting personal income to have grown 0.3% in April from March, a deceleration from 0.5% the previous month, and spending to have advanced 0.4%, half the 0.8% growth rate of March. 

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    Gistlegit
    Trending Video: How Mercyland Miracle Water Healed A Boy With Kidney Failure (WATCH VIDEO)
    ~1.8 mins read


    In a remarkable and awe-inspiring turn of events, a video has surfaced online showing a young boy named John miraculously healed of a severe kidney disease through the use of Prophet Jeremiah Fufeyin's miracle water. The video, which has now gone viral, has sparked widespread reactions and a renewed sense of hope among individuals battling various illnesses.
     
    The footage captures the emotional moment when John, frail and weak, was presented with the miracle water by Prophet Jeremiah Fufeyin himself. The boy, who had been suffering from kidney failure, underwent a tremendous transformation after drinking the water. Within moments, he began showing signs of improvement, with his energy levels surging and his health visibly improving.
     
    Watch Video:
     
    This extraordinary incident has further solidified Prophet Jeremiah Fufeyin's reputation as a renowned spiritual leader with genuine healing capabilities. Often referred to as one of the most anointed and benevolent prophets of our time, Prophet Jeremiah Fufeyin has become a beacon of hope for countless individuals seeking divine intervention.
     
    The news of this miraculous healing has resonated deeply with people from all walks of life, drawing attention to the power of faith and prayer. Many have taken to social media platforms to express their astonishment and gratitude for witnessing such a remarkable event. Hashtags such as #ProphetJeremiahFufeyinMiracleWater and #KidneyHealing have been trending, with users sharing their own stories of healing and redemption.
     
    Prophet Jeremiah Fufeyin's Miracle Water has already gained immense popularity and recognition for its healing properties. This latest incident serves as a testament to the divine mystique surrounding the water, further piquing the curiosity and faith of believers worldwide.

     
    Prophet Jeremiah Fufeyin has been known for his unwavering dedication to the cause of humanity and his efforts in transforming lives. His ministry, Christ Mercyland Deliverance Ministries, has become a sanctuary for the broken, desperate souls seeking solace and healing.
     
    As the news of this miraculous healing continues to spread like wildfire, it is clear that the impact of Prophet Jeremiah Fufeyin's miracle water reaches far beyond the boundaries of physical healing. It represents a glimmer of hope, a reminder that miracles can and do happen, and that divine intervention is always possible in the face of seemingly insurmountable odds.
     
    The world eagerly awaits more testimonies of healing and redemption as the phenomenon of Prophet Jeremiah Fufeyin's Miracle Water gains momentum. It is a time of celebration, faith, and hope for all those who have witnessed and experienced the transformative power of this remarkable spiritual elixir.
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    Instablog9ja
    Just In: President Tinubu Signs Bill Reverting To The Old National Anthem Into Law
    ~1.2 mins read

    President Bola Tinubu has assented to the National Anthem Bill 2024 reverting to the old national anthem, “Nigeria, we hail thee”.

    Senate President, Godswill Akpabio, revealed this on Wednesday at a joint session of the National Assembly marking the Silver Jubilee Of Nigeria’s 4th Republic. President Bola Tinubu is currently at the joint session.

    Akpabio said the sitting is primarily to launch the new national anthem, explaining that the President will not be making a speech because he has to leave to launch the Abuja metro line.

    The Senate and the House of Representatives had previously passed the legislation to swap the national anthem from “Arise, O Compatriots” to “Nigeria, We Hail Thee” at separate sittings. The old anthem, “Nigeria, We Hail Thee”, composed when Nigeria gained independence on October 1, 1960, has replaced the “Arise, O Compatriots” anthem.

    Lillian Jean Williams, a British expatriate who lived in Nigeria during its independence, penned the lyrics for “Nigeria, We Hail Thee,” while Frances Berda composed the music. The anthem played a significant role in shaping Nigeria’s national identity and unity during the 1960s and late 1970s.

    What are the lyrics to Nigeria We Hail Thee? Nigeria, we hail thee,
Our own dear native land,
Though tribe and tongue may differ,
In brotherhood, we stand,
Nigerians all, and proud to serve
Our sovereign Motherland. Our flag shall be a symbol
That truth and justice reign,
In peace or battle honour’d,
And this we count as gain,
To hand on to our children
A banner without stain. O God of all creation,
Grant this our one request,
Help us to build a nation
Where no man is oppressed,
And so with peace and plenty
Nigeria may be blessed.

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