Previous studies had shown faulty genes to be responsible for severe obesity that often occurs from a young age. This particular study, however, suggested that a combination of “thin” genes, or rather, the absence of “obesity-related genes” may help one to remain slim.

Human DNA is made up of a sequence of molecules called “base pairs.” The letters A, C, G, and T represent the base pairs, and strings of these make up the genetic regions. Our genes dictate how our bodies function, and variations, such as a C where an A should be, can have a subtle or dramatic influence on features such as eye color, hair color, and of course, weight.

The team came across several genetic variants that researchers had already identified and associated with obesity. However, the recent study found new genetic regions that could be responsible for healthy thinness.

When studying and comparing the DNA of the participants, Prof. Farooqi and his team came across several genetic variants that were previously identified for causing obesity. However, this recent study revealed new genetic regions, some of which are thought to be responsible for severe obesity, while others are thought to play a role in healthy thinness. To find out how genes affect one’s weight, the researchers took into account all the different genetic variants and came up with a genetic risk score.

As they suspected, obese people have a higher genetic risk score that makes them more likely to be overweight than people of normal weight. Thin people, on the other hand, have a significantly lower genetic risk score. They also lack the genetic variants that are known to be responsible for causing obesity. The study thus showed that people who have always been thin despite their diet and lifestyle choices have their unique genes to thank.

Though genes can determine a person’s weight, it does not mean one should forgo a healthy diet and lifestyle practices.

Do not let the results of the study fool you! You cannot simply give up on a healthy lifestyle just because you think your genes will act for or against you anyway. The study merely showed how genes may be responsible for different weight gain in different people. The odds may be stacked in favor of or against you. However, personal actions play a critical role when it comes to managing weight.

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