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Dementia usually develops in people ages 65 years and older. So-called young-onset dementia, occurring in those younger than age 65, is uncommon. Now, a new study published in December 2023 in JAMA Neurology has identified 15 factors linked to a higher risk of young-onset dementia.
Let's see what they found, and — most importantly — what you can do to reduce your own risks.
Are early dementia and young-onset dementia the same?
No. Experts think of early dementia as the first stage in dementia. Mild cognitive impairment and mild dementia are forms of early dementia. So, someone age 50, 65, or 88 could have early dementia.
Young-onset dementia refers to the age at which dementia is diagnosed. A person has young-onset dementia if symptoms and diagnosis occur before age 65.
What has previous research shown?
A previous study of men in Sweden identified some risk factors for young-onset dementia, including high blood pressure, stroke, depression, alcohol use disorder, vitamin D deficiency, drug use disorder, and overall cognitive function.
What to know about the new study
In the new study, a research team in the Netherlands and the United Kingdom looked at data from the UK Biobank. The biobank follows about half a million individuals in the United Kingdom who were 37 to 73 years old when they first joined the project between 2006 and 2010. Most participants identified as white (89%), and the remaining 11% were described only as "other." Slightly more than half of the participants (54%) were women.
The researchers excluded anyone age 65 or older and people who already had dementia at the start of the study, leaving 356,052 participants for the analyses. Over roughly a decade, 485 participants developed young-onset dementia. The researchers compared participants who did and did not develop young-onset dementia to identify possible risk factors.
What did the researchers learn about risks for young-onset dementia?
In reviewing the results, I think it is helpful to group the risk factors into several categories, and then to examine each of them. These risks may act on the brain directly or indirectly.
Eight factors that we know or strongly suspect cause dementia:
Two factors that reduce cognitive reserve
Cognitive reserve can be described as our capacity to think, improvise, and problem-solve even as our brains change with age. These two risk factors make it more likely that dementia symptoms will show up at a younger age.
Is every factor identified in the study a clear risk?
No, and here's why not: Sometimes research turns up apparent risk factors that might be due to reverse causation. It's possible, for example, that symptoms of impending dementia appear to be risk factors because they become noticeable before obvious dementia is diagnosed.
Lastly, there are risk factors that could be either a contributing cause or a result of the impending dementia.
What can you do to prevent young-onset dementia?
Taking these five steps can reduce your risk for developing dementia before age 65:
Source: Harvard Health Publishing
Instablog9ja
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The Nigerian government has cautioned Nigerians not to engage in panic buying of petrol, saying it has sufficient product in the country.
Heineken Lokpobiri, Minister of State for Petroleum Resources (Oil) disclosed this in a statement posted on his X handle on Thursday.
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Nigerian brothers, Samuel Ogoshi, 24, and Samson Ogoshi, 21, has been sentenced to 18 years imprisonment in the United States for their role in a s+xtortion scheme that tragically claimed the life of 17-year-old Jordan DeMay from Michigan.
The U.S. Attorney for the Western District of Michigan Mark Totten also ordered that the convicts will undergo five years of supervised release after they served their time.
On March 25, 2022, 17-year-old high school student, Jordan DeMay, from Marquette, Michigan, di3d as a result of this s+xtortion scheme, which targeted over 100 other victims, as well.
Speaking at the sentencing, U.S. Attorney Mark Totten said: “Today’s sentencing of Samuel and Samson Ogoshi sends a thundering message to crim+nals who commit these schemes: you are not immune from justice. We will track you down and hold you accountable, even if we have to go half-way around the world to do so. The day when you could commit these crimes, rake in easy cash, d£§troy lives, and escape justice is gone.
And to parents, teenagers, and everyone who uses a cell phone: please, please be careful. These devices can connect you to crim+nal networks around the world. Don’t assume people are who they say they are. Don’t share compromising images. And if you’re a victim, please reach out. There’s help, and law enforcement stands ready.”
Samuel and Samson Ogoshi used hacked social media accounts to pose as young women and solicited explicit images from victims.
They thr£@tened to share these images with the victims’ family and friends unless they paid money, this was contained in a press release from the office of the United States Anthony’s Office.
In November 2022, the U.S. Attorney’s Office charged the Ogoshi brothers and another Nigerian, Ezekiel Robert, in connection with the scheme. Ezekiel Robert is currently appealing his extradition to the U.S.
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New details have emerged regarding Ugandan athlete Rebecca Cheptegei who passed away after being s3t abl@ze by her boyfriend, Dickson Ndiema.
Local news reports that Ndiema entered Cheptegei’s home while she and her two children were at church on Sunday, September 2.
He was said to have dou§£d her with gasoline before s3tting her alight. He was also engulfed by the flames and rushed to hospital. He was b¥rned over 30 percent of his body and is reportedly in the intensive care unit recuperating.
The gruesome att@ck occurred in the presence of the runner’s two daughters, aged 11 and nine. During the att@ck, one of them rushed to her aid but was reportedly a§§aulted by Ndiema.
“He ki+ked me while I tried to run to the rescue of my mother. I immediately cried out for help, attracting a neighbor who tried to extinguish the flames with water, but it was not possible,” she told newsmen.
Cheptegei’s two children are not fathered by Ndiema.
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Investopedia
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As job openings become more difficult to come by and the unemployment rate increases, more people are worried about job stability.
A Wednesday report showed the fewestjob openings per unemployed worker since mid-2021. Workers will also watch for an update to the unemployment rate on Friday, waiting to see if the measure will continue its four-month streak of increases.
The cracks in the labor market are starting to wear on employees, who reported their likelihood of becoming unemployed rose to the highest level ever recorded in a Federal Reserve Bank of New York survey dating back to 2014. The survey also found employees' dissatisfaction with jobs is also growing, with more looking for a new position.
Experts said putting money aside in a high-yield savings account and assessing where your money is going may be the best way to quickly build up a financial cushion in case of job loss or change.
Financial experts say you should have an emergency fund to cover your expenses for three to six months. However, as hiring is slowing and everyday prices are inflated, that amount of time may need to be adjusted higher, they said.
"The individual's risk tolerance and expectations around the time it might take to find a new position should help to determine a savings target," said Eddy Jurgielewicz, partner and financial planner at Upbeat Wealth in an email.
Experts suggested putting emergency funds into a high-yield savings account to build up an emergency fund quickly. They said that neo-banks, or banks that only exist online, typically offer higher yield rates.
According to Investopedia's research, some high-yield savings accounts have rates as high as 5.50%. However, some accounts with high interest rates have minimum balances or a monthly fee.
“There are a lot of high-yield savings accounts that will advertise a certain rate, but they may jump through a bunch of hoops to get that particular rate,” said Sarah Paulson, a certified financial planner with Valkyrie Financial. “So always be reading the fine print or the little asterisks."
Reassessing where your money is going may also help you save more money and prepare to live leaner if you have to look for a new job.
Financial planners advise making a detailed budget to evaluate where you spend money and eliminate unnecessary expenses. There may also be other wiggle room in your budget, said Crystal McKeon, chief compliance officer and certified financial planner at TSA Wealth Management.
"Go price shopping on your big expenses like home, car and health insurance," McKeon wrote in an email. "If you can find something cheaper, the savings could be big."
If you're very concerned, experts said there may be other measures you can take—but they often come with trade-offs.
"This may be an instance where we would consider reducing contributions to other accounts," Jurgielewicz said. "We might look at the option of temporarily putting less into the 401(k) so that they're able to shift more into their liquid savings. Of course, there are always a lot of factors at play so we would need to assess all the trade-offs being presented."
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Investopedia
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Shares of Zimmer Biomet Holdings (ZBH) dropped nearly 9% after the manufacturer of artificial joint replacements and other orthopedic products warned the implementation of a new enterprise resources planning (ERP) system would hit sales and profits in 2024.
In a presentation Thursday at the Wells Fargo 2024 Healthcare Conference, Zimmer executives said the company switched from a legacy ERP platform to one from SAP, a transition that has run into complications. Zimmer's management team expects the issue to cause a 1% drag on revenue this year, with the headwinds mostly abating by the end of the fourth quarter.
ERP software aims to integrate business processes — from inventory tracking and sales to human resources and beyond. Zimmer's ERP transition is reportedly causing production issues and impeding shipments, especially in its sports, extremities, and trauma segments.
Analysts at Stifel predicted a potential 210-basis-point impact on third-quarter sales from the ERP transition, exacerbating what is already a difficult market environment. Meanwhile, Evercore ISI analysts said the issue could reduce earnings per share (EPS) by 15 cents.
Zimmer Biomet shares had been trending higher since Aug. 7, when the company released its second-quarter results and announced an agreement to acquire OrthoGrid Systems, which specializes in artificial intelligence guidance systems for hip replacement surgery.
Thursday's losses reversed those post-earnings gains. Zimmer Biomet stock is down about 14% year to date.
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